Research Article
Open Access
Hyperfine Nano-Structural investigations of Solid Phase Cefixime Antibiotic Drug
Khaled M. Elsabawy1,2
1Materials Science Unit, Chemistry Department, Faculty of Science, Tanta University-31725
Tanta –Egypt
2Department of Chemistry, Faculty of Science, Taif University, 888—Zipcode 21974- Taif,
Saudi Arabia
Khaled M. Elsabawy /Int.J Chemical Concepts 2015,1(1), pp 38-43.
Abstract
It well known that cefixime, an antibiotic, is a third-generation cephalosporin
like ceftriaxone and cefotaxime. Cefixime is highly stable in the presence of beta
lactamase enzymes. As a result, many organisms resistant to penicillins and some
cephalosporins due to the presence of beta-lactamases, may be susceptible to cefixime.
For these importance, we introduce hyperfine nano-structural features for cefixime via
high resolution 3D-AFM-investigations to understand how this hetero-molecule is
suitable structurally to their function as antibacterial antibiotic.
Keywords
3D-AFM; XRD; Cefixime; Microstructure; Grain Size; Antibacterial.
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